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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: Pharmacol Biochem Behav. 2010 May 15;97(1):138–143. doi: 10.1016/j.pbb.2010.05.010

Figure 4.

Figure 4

Bupropion, but not MSI-1436 or saline, decreases the rate of decay from peak evoked DA release. The time for evoked DA release to fall to 50% of its peak value (Halflife) was measured once every 5min. Halflife was normalized for each rat and expressed as percent change from the average of the 3 baseline samples. The known reuptake blocker bupropion (filled circles) significantly increased Halflife from 20 min after injection through the duration of the experiment. Injection of either saline (open circles) or MSI-1436 (closed squares) had no effect on Halflife. Data points represent group means and error bars denote ±1S.E.M.