Table 4.
Comparative Performance of Depression Rating Scales at First Visit vs. Subsequent Visits
Rating Scale | Epocha | First Visits (n=356) |
Subsequent Visits (n=2474) |
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SCID MDE Criteria | AUC of ROC | Optimal Cut-pointb | Sensitivity & Specificity | SCID MDE Criteria | AUC of ROC | Optimal Cut-pointb | Sensitivity & Specificity | ||||||||
Yes | No | Total | Sens. | Spec. | Yes | No | Total | Sens. | Spec. | ||||||
HRSD17 | PC | 6 | 51 | 0.851 | 15 | 1.696 | 0.833 | 0.863 | 10 | 150 | 0.990 | 16 | 1.947 | 1.000 | 0.947 |
T1 | 38 | 84 | 0.862 | 15 | 1.630 | 0.868 | 0.762 | 20 | 201 | 0.849 | 14 | 1.551 | 0.750 | 0.801 | |
T2 | 52 | 80 | 0.880 | 15 | 1.629 | 0.904 | 0.725 | 67 | 465 | 0.857 | 14 | 1.570 | 0.761 | 0.809 | |
T3 | 21 | 21 | 0.861 | 15 | 1.571 | 0.905 | 0.667 | 42 | 403 | 0.847 | 13 | 1.575 | 0.833 | 0.742 | |
Overall | 117 | 236 | 0.877 | 15 | 1.648 | 0.889 | 0.759 | 139 | 1219 | 0.866 | 14 | 1.595 | 0.784 | 0.811 | |
HRSD21 | PC | 6 | 50 | 0.832 | 15 | 1.693 | 0.833 | 0.860 | 10 | 150 | 0.986 | 17 | 1.960 | 1.000 | 0.960 |
T1 | 38 | 83 | 0.856 | 16 | 1.599 | 0.816 | 0.783 | 20 | 200 | 0.843 | 13 | 1.575 | 0.850 | 0.725 | |
T2 | 52 | 79 | 0.886 | 17 | 1.630 | 0.808 | 0.823 | 67 | 461 | 0.856 | 15 | 1.579 | 0.761 | 0.818 | |
T3 | 21 | 20 | 0.856 | 22 | 1.614 | 0.714 | 0.900 | 42 | 403 | 0.846 | 16 | 1.587 | 0.738 | 0.849 | |
Overall | 117 | 232 | 0.876 | 15 | 1.610 | 0.889 | 0.721 | 139 | 1214 | 0.864 | 15 | 1.592 | 0.770 | 0.822 | |
BDI | PC | 6 | 46 | 0.846 | 12 | 1.652 | 1.000 | 0.652 | 10 | 148 | 0.982 | 17 | 1.932 | 1.000 | 0.932 |
T1 | 33 | 72 | 0.877 | 18 | 1.654 | 0.848 | 0.806 | 19 | 187 | 0.871 | 15 | 1.666 | 0.842 | 0.824 | |
T2 | 42 | 68 | 0.866 | 19 | 1.626 | 0.714 | 0.912 | 58 | 423 | 0.901 | 13 | 1.683 | 0.879 | 0.804 | |
T3 | 17 | 17 | 0.824 | 12 | 1.588 | 0.941 | 0.647 | 34 | 353 | 0.857 | 12 | 1.566 | 0.824 | 0.742 | |
Overall | 98 | 203 | 0.871 | 19 | 1.587 | 0.735 | 0.852 | 121 | 1111 | 0.893 | 13 | 1.646 | 0.851 | 0.795 | |
EPDS | PC | 0 | 8 | NAc | NA | NA | NA | NA | 6 | 49 | 0.998 | 16 | 1.980 | 1.000 | 0.980 |
T1 | 11 | 20 | 0.868 | 17 | 1.636 | 0.636 | 1.000 | 10 | 73 | 0.928 | 13 | 1.690 | 0.800 | 0.890 | |
T2 | 12 | 23 | 0.873 | 17 | 1.580 | 0.667 | 0.913 | 23 | 165 | 0.860 | 6 | 1.533 | 1.000 | 0.533 | |
T3 | 0 | 1 | NA | NA | NA | NA | NA | 6 | 101 | 0.959 | 15 | 1.814 | 0.833 | 0.980 | |
Overall | 23 | 52 | 0.849 | 17 | 1.614 | 0.652 | 0.962 | 45 | 388 | 0.907 | 13 | 1.623 | 0.733 | 0.889 |
Perinatal Epochs: PC=preconception; T1=first trimester; T2=second trimester; T3=third trimester
Optimal Cutpoint: The cutpoint is the score such that greater or equal scores are considered consistent with the presence of a major depressive episode. The optimal cutpoint is the cutpoint score that maximizes the sum of sensitivity and specificity.
Not applicable when the number of subjects satisfying MDE criteria is 0.