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(a) Alignment of the amino acid sequences of ApPolη and HsPolη (NP_006493.1). Identical and similar residues between the two enzymes are indicated in black and grey, respectively. (b) Phylogenetic analysis of TLS polymerases. A phylogenetic tree was constructed by the UPGMA method, based on the amino acid sequences of the ApPolη and other Y- and B-family DNA polymerases.
