Table 1.
Strain virulence in the mouse infection model (BALB/c)
| Strain | Inoculum (cfu) | Mortality 4 days post infection | Mortality 13 days post infection |
|---|---|---|---|
| PBS | 0 | 0/6 | 0/6 |
| BpK96243 | 9 | 0/6 | 0/6 |
| 118 | 0/6 | 4/6 (66.7%) | |
| 380 | 0/6 | 4/6 (66.7%) | |
| 1180 | 0/6 | 5/6 (83%) | |
| 3600 | 1/6 (16.7%) | 6/6 (100%) | |
| Bp22 | 6 | 0/6 | 2/6 (33%) |
| 19 | 0/6 | 5/6 (83%) | |
| 58 | 0/6 | 5/6 (83%) | |
| 175 | 1/6 (16.7%) | 6/6 (100%) | |
| 525 | 2/6 (33%) | 6/6 (100%) | |
| BtE264 | 1000 | 0/6 | 0/6 |
| 104 | 0/6 | 0/6 | |
| 105 | 0/6 | 0/6 | |
| 106 | 0/6 | 0/6 | |
| 107 | 1/6 (16.7%) | 1/6 (16.7%) | |
| BtE555 | 1,000 | 0/6 | 0/6 |
| 104 | 0/6 | 0/6 | |
| 105 | 0/6 | 0/6 | |
| 106 | 0/6 | 0/6 | |
| 107 | 4/6 (66.7%) | 4/6 (66.7) |
Infection assays in BALB/c mice. Mice were monitored for up to 13 days post-infection with different starting amounts of bacteria (cfu column). Note the differences in cfu between Bp and Bt strains (starting cfu 6 to 9 versus 1,000). PBS, phosphate-buffered saline.