Table 1.
Difference in Various Baseline Characteristics Between Those Included and Excluded from Analyses in the Renin-Angiotensin System Study
| Included | Excluded | |||||||
|---|---|---|---|---|---|---|---|---|
| Characteristic | N | Mean (%) | SD | N | Mean (%) | SD | P-value* | Age-adjusted P-value† |
| Age (years) | 147 | 31.33 | 9.33 | 138 | 27.88 | 9.89 | 0.003 | |
| Male gender | 67 | 45.8 | 65 | 47.1 | 0.80 | 0.38 | ||
| Glycosylated hemoglobin (%) | 147 | 8.49 | 1.55 | 137 | 8.65 | 1.59 | 0.39 | 0.67 |
| Body mass index (kg/m2) | 147 | 26.11 | 3.92 | 138 | 25.28 | 3.39 | 0.06 | 0.09 |
| Clinic SBP (mmHg) | 147 | 119.78 | 12.04 | 138 | 119.54 | 10.99 | 0.87 | 0.51 |
| Clinic DBP (mmHg) | 147 | 70.57 | 8.20 | 138 | 69.76 | 8.56 | 0.41 | 0.74 |
| Clinic MABP (mmHg) | 147 | 86.98 | 8.58 | 138 | 86.36 | 8.45 | 0.54 | 0.60 |
| Clinic pulse pressure (mmHg) | 147 | 49.20 | 9.38 | 138 | 49.78 | 8.92 | 0.59 | 0.61 |
| Ambulatory pulse (beats/min) | 115 | 77.38 | 9.30 | 100 | 80.52 | 8.68 | 0.01 | 0.06 |
| Ambulatory 24-hour SBP (mmHg) | 115 | 117.84 | 8.77 | 100 | 118.92 | 8.87 | 0.37 | 0.20 |
| Ambulatory 24-hour DBP (mmHg) | 115 | 71.41 | 5.41 | 100 | 72.22 | 5.95 | 0.30 | 0.09 |
| Ambulatory daytime SBP (mmHg) | 115 | 121.95 | 9.66 | 100 | 122.94 | 9.82 | 0.46 | 0.18 |
| Ambulatory daytime DBP (mmHg) | 115 | 75.44 | 6.16 | 100 | 76.39 | 7.12 | 0.30 | 0.08 |
| Ambulatory nighttime SBP (mmHg) | 115 | 111.17 | 9.66 | 100 | 111.65 | 8.85 | 0.71 | 0.60 |
| Ambulatory nighttime DBP (mmHg) | 115 | 65.34 | 6.94 | 100 | 65.13 | 7.11 | 0.83 | 0.81 |
| CRAE (μm) | 147 | 158.43 | 13.58 | 110 | 159.71 | 12.59 | 0.44 | 0.83 |
| CRVE (μm) | 147 | 227.03 | 21.22 | 110 | 229.47 | 23.29 | 0.38 | 0.81 |
| Current smoker | 37 | 25.2 | 35 | 25.4 | 0.97 | 0.99 | ||
| Non-dipper status | 32 | 21.8 | 25 | 18.1 | 0.44 | 0.55 | ||
| Treatment | ||||||||
| Placebo | 48 | 34.7 | 44 | 31.9 | 0.87 | 0.80 | ||
| Enalapril | 48 | 32.7 | 46 | 33.3 | ||||
| Losartan | 51 | 32.6 | 48 | 34.8 | ||||
| Diabetic retinopathy | ||||||||
| None | 54 | 36.8 | 35 | 31.8 | 0.37 | 0.38 | ||
| Mild nonproliferative | 75 | 51.0 | 67 | 60.9 | ||||
| Moderate to severe nonproliferative | 15 | 10.2 | 7 | 6.4 | ||||
| Proliferative | 3 | 2.0 | 1 | 0.9 | ||||
*
P-value is for t-test for difference in means between continuous variables and chi-square test for categorical variables.
†
P-value is for t-test for differences in means between continuous variables, adjusted for age, and for the Cochran-Mantel-Haenszel test of general association for categorical variables.
Abbreviations: CRAE = central retinal arteriole equivalent; CRVE = central retinal venule equivalent; SBP=systolic blood pressure; DBP=diastolic blood pressure; MABP= mean arterial blood pressure.