Table 4. Associations Between the POMS-Scale Arousal and Fatigue and FAAH three-SNP Haplotypes from rs3766246, rs324420, and rs2295633.

Haplotypes (10-mg dose)	Betaa	R2b	STATc	NPd	Corr. Emp. p-valuee
Arousal
TAT (Ff=0.102)	−3.847	0.016	−1.620	168	0.0947
TCT (F=0.0807)	−1.388	0.002	−0.572	7	0.75
CCC (F=0.485)	3.682	0.023	1.941	300	0.0565
Fatigue
TAT (Ff=0.102)	2.217	0.031	2.238	826	0.0206*
TCT (F=0.0807)	0.687	0.002	0.674	10	0.5625
CCC (F=0.485)	−2.054	0.041	−2.601	2316	0.0078**

FAAH, fatty acid amide hydrolase; POMS, Profile of Mood States.

^aRegression coefficient.

^bProportion of phenotypic variability explained by haplotype.

^cWald test (based on t-distribtion).

^dNumber of permutations performed for this haplotype.

^eEmpirical p-value (adaptive).

^fFrequency.

^*p<0.05.

^**p<0.01.