Table 1.

CDR of 2 at −45 °C for 3 h using ligand 8 (or 9 where noted).

Entry	E+	Product(s)	% Yield	er
1	Me3SiCl	(S)-3	74	96:4
2	Bu3SnCl	(S)-10	66	96:4
3	Bu3SnCl	(R)-10	62	97:3a
4	CO2	(R)-11	78	98:2
5	MeOCOCl	(R)-12	88	>99:1
6	MeOCOCl	(S)-12	85	>99:1a
7	PhNCO	(R)-13	68	>99:1
8	Allyl bromide	(R)-14	63	95:5b
9	Allyl bromide	(S)-14	59	96:4a,b
10	BnBr	(R)-15	65	>99:1b
11	Cyclohexanone	(R)-16	60	94:6
12	PhCHOc	17	74 (62:38 dr)	>99:1 & 98:2
13	1-NpCHOc	18	66 (82:18 dr)	94:6 & 93:7
14	CH3CHOc	19	78 (85:15 dr)	>99:1 for both

^aUsing ligand 9

^bvia Negishi cross coupling

^cMajor diastereomer illustrated