Table 4.
Clinical, Laboratory, and Hemodynamic Characteristics According to hs-CRP Tertile
| hs-CRP tertiles | ||||
|---|---|---|---|---|
| Demographics | Low risk (<1 mg/L) | Avg risk (1–3)mg/L | High risk (> 3mg/L) | P value |
| Age, years | 52.90± 7.30 | 54.30± 6.00 | 51.30± 5.40 | 0.520 |
| BMI(kg/m2) | 28.60± 3.40 | 31.60± 6.50 | 34.20 ± 4.00 | 0.040 |
| Total Cholesterol(mg/dL) | 203.00 ± 24.60 | 182.00± 25.20 | 191.50 ±27.60 | 0.239 |
| Triglycerides(mg/dL) | 80.50± 24.00 | 91.70± 47.00 | 85.50± 27.00 | 0.779 |
| LDL-C(mg/dL) | 110.00 ± 33.50 | 105.00± 21.20 | 114.70 ±25.70 | 0.696 |
| HDL-C(mg/dL) | 76.90± 26.00 | 58.70 ± 10.70 | 59.60± 10.60 | 0.036 |
| Serum Creatinine(mg/dL) | 0.79 ±0.12 | 0.81 ± 0.09 | 0.87 ± 0.17.00 | 0.541 |
| Clinic Systolic BP (mmHg) | 116.70 ±10.6 | 124.80 ± 5.90 | 127.7±13.30 | 0.077 |
| Clinic Diastolic BP(mmHg) | 72.40± 6.20 | 79.90± 5.30 | 80.30 ± 6.70 | 0.010 |
| HR(bpm) | 78.00± 3.40 | 79.30± 8.20 | 86.8 ± 5.10 | 0.138 |
| Hemoglobin(g/dL) | 13.10± 0.14 | 13.20 ± 0.11 | 13.40± 13.00 | 0.482 |
| WBC (103/μL) | 5.90± 2.20 | 4.50± 0.74 | 5.30± 1.40 | 0.359 |
| hs-CRP(mg/L) | 0.71 ± 0.25 | 1.95± 0.48 | 5.57 ± 1.70 | 0.000 |
| TNF-α(pg/ml) | 27.10± 20.6 | 44.70 ± 17.30 | 59.70± 23.50 | 0.276 |
| ABP parameters | ||||
| 24-hr SBP(mmHg) | 118.80± 9.50 | 129.60 ±10.30 | 127.80 ±12.30 | 0.089 |
| 24-hr DBP(mmHg) | 71.80± 5.90 | 83.70± 7.10 | 77.70± 9.50 | 0.010 |
| 24-hr MAP(mmHg) | 88.40± 6.50 | 99.24 ± 7.50 | 95.20± 9.70 | 0.020 |
| 24-hr HR(bpm) | 71.50± 10.50 | 74.80± 11.50 | 77.20± 8.10 | 0.434 |
| Awake SBP(mmHg) | 120.80 ±10.50 | 131.00± 11.30 | 130.10 ±13.30 | 0.144 |
| Awake DBP(mmHg) | 73.80 ± 6.90 | 85.80± 8.00 | 79.60± 9.70 | 0.020 |
| Awake MAP(mmHg) | 90.50± 7.70 | 100.90± 8.00 | 97.30± 10.10 | 0.059 |
| Awake HR(bpm) | 73.40± 10.90 | 77.60± 12.50 | 78.80± 8.20 | 0.486 |
| Sleep SBP(mmHg) | 110.40± 8.60 | 118.80± 7.50 | 119.70± 10.00 | 0.057 |
| Sleep DBP(mmHg) | 63.60± 5.00 | 71.20± 5.30 | 71.10± 10.10 | 0.062 |
| Sleep MAP(mmHg) | 79.80± 5.20 | 87.20± 5.70 | 88.30± 9.60 | 0.040 |
| Sleep HR(bpm) | 64.20± 9.60 | 68.30± 11.30 | 71.60± 9.30 | 0.251 |
| Average Real Variability | ||||
| 24-hr systolic ARV(mmHg) | 7.20± 0.67 | 8.30± 1.40 | 8.80± 1.10 | 0.014 |
| 24-hr diastolic ARV(mmHg) | 5.90± 0.93 | 7.40± 1.50 | 7.50± 0.77 | 0.006 |
| 24-hr MAP AR (mmHg) | 6.10± 1.00 | 7.50± 1.70 | 8.00± 1.00 | 0.007 |
| 24-hr HR ARV(bpm) | 7.40 ± 1.70 | 7.50 ± 2.00 | 6.50± 2.20 | 0.477 |
| Awake systolicARV (mmHg) | 7.20± 0.94 | 7.90± 1.30 | 8.50± 1.20 | 0.041 |
| Awake diastolic ARV(mmHg) | 5.60± 0.81 | 7.20± 1.60 | 7.40± 1.00 | 0.010 |
| Awake MAP ARV(mmHg) | 6.05 ± 1.20 | 7.20± 1.50 | 7.80± 0.90 | 0.010 |
| Awake HR ARV(bpm) | 7.60± 1.80 | 7.70± 2.40 | 6.80 ± 2.40 | 0.560 |
| Sleep systolic ARV(mmHg) | 7.30± 2.00 | 8.40± 3.80 | 9.50± 2.70 | 0.241 |
| Sleep diastolic ARV(mmHg) | 6.80± 2.20 | 7.60± 4.40 | 6.60± 2.80 | 0.768 |
| Sleep MAP ARV(mmHg) | 6.00± 2.40 | 8.30± 4.80 | 7.50± 2.00 | 0.302 |
| Sleep HR ARV(bpm) | 6.00± 3.80 | 6.10± 4.20 | 7.50± 2.00 | 0.766 |
Data are expressed as mean ± SEM unless otherwise indicated;
*
, p < 0.0.5
hs-CRP, high sensitivity C-reactive Protein; ARV, Average Real Variability; Avg, Average; SBP, systolic BP, DBP, diastolic BP; HR, heart rate.