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. 2010 Sep 1;4:121. doi: 10.1186/1752-0509-4-121

Table 1.

Cliques of Dt with corresponding p-values for BCR pathway

H0 : Σ1 = Σ2 H0 : μ1 = μ2
Clique p-value p-value

(PLCG2, SYK, BTK, BLNK) 0.056 0.122
(PLCG2, SYK, PI3K) 0.164 0.075
(PLCG2, CaN) 0.988 0.023
(PLCG2, SOS, BLNK) 0.570 0.008
(PLCG2, SOS, RaSGRP3) 0.715 0.013
(PLCG2, PKCB, BCL10) 0.942 0.002
(PLCG2, BCL10, PI3K) 0.796 0.059
(CD72, CD22, SHP1) 0.026 0.000
(LYN, SYK, BTK, BLNK) 0.008 0.549
(LYN, SYK, BTK, SHP1) 0.000 0.475
(LYN, CD79) 0.832 0.780
(LYN, CD19) 0.989 0.358
(LYN, VAV, BLNK) 0.920 0.696
(LYN, VAV, RAC) 0.336 0.141
(NFAT, CaN) 0.529 0.002
(GRB2, BLNK, SOS) 0.821 0.201
(Ras, RaSGRP3) 0.044 0.121
(Ras, Raf) 0.243 0.182
(Raf, MEK1/2) 0.101 0.825
(MEK1/2, ERK) 0.252 0.593
(ERK, AP1) 0.028 0.026
(IKK, BCL10, AKT) 0.430 0.524
(IKK, IKB, NFKB) 0.547 0.002
(AKT, PI3K, BCL10) 0.476 0.142
(AKT, PI3K, SHIP) 0.558 0.215
(AKT, GSK3B) 0.631 0.017
(CD81, SYK, PI3K) 0.395 0.193
(SHIP, FcgRIIB) 0.980 0.443
LEU13 0.103 0.003
CD21 0.008 0.008

Cliques of the triangulated graph Dt with corresponding p-values for the BCR pathway. The first column refers to the test (1), the second one to the test (2). The p-values in italics in the second column are exact, i.e., are computed on the exact null distribution of the test statistics.