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. 2010 Sep 13;9:240. doi: 10.1186/1476-4598-9-240

Figure 1.

Figure 1

t-DARPP is overexpressed in primary breast tumors. A, normal adjacent (n = 18) and tumor (n = 36) breast tissue samples were analyzed by quantitative real time RT-PCR for t-DARPP mRNA expression. RT-PCR results were normalized with the internal control genes β-actin and HPRT1. The results were plotted as a ratio of normalized t-DARPP mRNA expression by the average of normalized t-DARPP mRNA expression of normal samples. Overexpression of t-DARPP was detected in 36% of breast tumors relative to normal tissue samples (p < 0.05). B, the overexpression of t-DARPP was overwhelmingly observed in ductal carcinomas (p = 0.06), including invasive ductal carcinomas and intraductal carcinomas, as opposed to other types of breast cancers. The other types of breast cancers include 1 invasive lobular carcinoma, 1 mucinous carcinoma, 1 apocrine carcinoma and 3 undifferentiated carcinomas. Horizontal bars indicate mean values. Mann Whitney test was used for statistical analysis in A and B.