Table 4.

Mean IOP and mean change in IOP from baseline to last visit* (mmHg), alternate populations

Visit	n	Mean ± SD (95% CI)	Change from baseline, mean ± SD (95% CI†)
PP population: corrected IOP[17]
Baseline	546	20.5 ± 3.94	n.a.
		(20.2, 20.9)
Last visit	546	16.3 ± 3.30	-4.2 ± 4.21
		(16.0, 16.6)	(-4.6, -3.9)
Full analysis set: raw IOP
Baseline	1913	20.4 ± 4.25	n.a.
		(20.2, 20.6)
Last visit	1934	16.4 ± 3.42	-3.9 ± 4.65‡
		(16.3, 16.6)	(-4.2, -3.7)
PP population with applanation tonometry data: raw IOP
Baseline	732	20.3 ± 4.31	n.a.
		(20.0, 20.6)
Last visit	687	16.2 ± 3.02	-4.0 ± 4.59§
		(16.0, 16.4)	(-4.3, -3.6)

CI = confidence interval; IOP = intraocular pressure; n.a. = not applicable; PP = per protocol;

SD = standard deviation.

*Last visit = last postbaseline visit at which an IOP level was recorded.

^†P < 0.05 for change from baseline to last visit for each parameter.

^‡N = 1913.

^§N = 631.