Table 3.
Ontological classifications of gene expression alterations by Libby six-mix (15×106 μm2/cm2) in LP9/TERT-1 human mesothelial cells at 24 h
| Ontological Classification | No. Genes Upregulateda | No. Genes Downregulated |
|---|---|---|
| Signal transduction | 17 | 10 |
| Immune response | 8 | 1 |
| Protein metabolic process | 7 | 5 |
| Apoptosis regulation | 4 | 4 |
| Cell proliferation | 8 | 2 |
| Extracellular matrix | 2 | 1 |
| Cell adhesion | 2 | 2 |
| Cell motility | 2 | 0 |
| Oxygen & ROS metabolic process | 1 | 0 |
a Overall, 74 genes were upregulated and 37 genes were downregulated ( > 2-fold compared to untreated controls; p < 0.05), although only the most common ontological classifications are given.