Figure 1.
(A) shows the PLGA scaffolds made of PLGA IV 1.13, PLGA concentration 12.5% and (left) dry control, (middle) wet control, (right) scaffold incubated with fibroblasts for 3 weeks. The PLGA scaffold was contracted by fibroblasts after incubation for 3 weeks. (B) shows the same polymer with a calcium phosphate particulate inclusion phase [CaP/PLGA ratio 2:1]: (left) dry control, (middle) wet control, (right) scaffold incubated with fibroblasts for 3 weeks. The CaP/PLGA composite scaffold retained its original shape in the presence of cultured cells. )A + B from reference Guan & Davies.2) (C) Compressive Modulus of uncoated and coated scaffold. Mean ± SD. Data courtesy of Limin Guan.