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. Author manuscript; available in PMC: 2011 Apr 1.
Published in final edited form as: Nat Chem. 2010 Aug 1;2(10):886–892. doi: 10.1038/nchem.794

Figure 7. Chemical interconversions among intermediates of cortistatin series A, J, and L and a hypothesized parallel biosynthetic sequence.

Figure 7

Intermediates of the cortistatin L series are found to undergo facile laboratory transformations to form corresponding intermediates of the A and J series, suggesting a plausible sequencing for the latter stages of cortistatin biosyntheses, which are unknown. Ms = methanesulfonyl.