1 |
cortistatin A (1) |
2 |
cortistatin J (2) |
3 |
cortistatin K (3) |
4 |
cortistatin L (4) |
5 |
azido alcohol 5
|
6 |
cyclohexatrienone 6
|
7 |
triene 7
|
8 |
o –vinyl benzylzinc reagent 8
|
9 |
enol triflate 9
|
10 |
methyl 5-hydroxy-2-iodobenzoate (10) |
11 |
methyl 2-iodo-5-(triisopropylsilyloxy)benzoate (11) |
12 |
methyl 5-(triisopropylsilyloxy)-2-vinylbenzoate (12) |
13 |
(5-(triisopropylsilyloxy)-2-vinylphenyl)methanol (13) |
14 |
(3-(bromomethyl)-4-vinylphenoxy)triisopropylsilane (14) |
15 |
α-methylene ketone 15
|
16 |
triethylsilyl enol ether phosphonium salt 16
|
17 |
triethylsilyl dienol ether 17
|
18 |
tetracyclic diene 18
|
19 |
tetracyclic diene monoepoxide 19
|
20 |
tetracyclic epoxide 20
|
21 |
allylic alcohol 21
|
22 |
bromo ketone 22
|
23 |
chloroacetate ester 23 (cortistatin A series) |
24 |
dienyl keto alcohol 24 (cortistatin A series) |
25 |
allylic bromide 25 (cortistatin A series) |
26 |
trans diol methyl ether 26 (cortistatin A series) |
27 |
dienyl azido diol 27 (cortistatin A series) |
28 |
dimethylamino keto diol 28 (cortistatin A series) |
29 |
dimethylamino ketone 29 (cortistatin A series) |
30 |
dimethylamino alcohol 30 (cortistatin J and K series) |
31 |
trienyl alcohol 31 (cortistatin J series) |
32 |
dimethylamino ketone 32 (cortistatin J series) |
33 |
acetate 33 (cortistatin K series) |
34 |
tert- butyldimethylsilyl ether 34 (cortistatin K series) |
35 |
dimethylamino ketone 35 (cortistatin K series) |
36 |
azido tert -butyldimethylsilyl ether 36 (cortistatin L series) |
37 |
dimethylamino alcohol 37 (cortistatin L series) |
38 |
dimethylamino ketone 38 (cortistatin L series) |
39 |
7-lithioisoquinoline (39) |
40 |
isoquinolyl alcohol 40 (cortistatin A series) |
41 |
isoquinolyl alcohol 41 (cortistatin L series) |
42 |
isoquinolyl alcohol 42 (cortistatin J series) |
43 |
isoquinolyl alcohol 43 (cortistatin K series) |
44 |
trienyl tert- butyldimethylsilyl ether 44
|
45 |
dienyl bromo triethylsilyl ether 45
|
46 |
allylic epoxide 46
|
47 |
dienyl alcohol 47
|
48 |
5-hydroxy-2-iodobenzoic acid (48) |
49 |
7-isoquinolyl trifluoromethylsulfonate (49) |
50 |
7-trimethylstannylisoquinoline (50) |
51 |
7-iodoisoquinoline (51) |
52 |
cortistatin A bis(triethylsilyl) ether (52) |
53 |
dimethylamino alcohol 53 (cortistatin K series) |
54 |
dienyl diol 54 (cortistatin L series) |
55 |
cortistatin L tert -butyldimethylsilyl ether (55) |