Figure 2.

Low-sodium diet expands TUF1 expression in the zona glomerulosa. A–C, Adrenal sections from control (A), low-sodium diet (B), and sodium-repleted (C) rats labeled for AS (green) and TUF1 (red). In addition to the zona glomerulosa, TUF1 was expressed in cell clusters in the zona fasciculata of control adrenals (A, arrow) and in the outer fasciculata after sodium repletion (C); after sodium repletion, TUF1 expression remained elevated in the glomerulosa (C, inset, arrow) relative to the underlying fasciculata. Adrenal capsule (cap) and zona glomerulosa (zg) are indicated. Width of zona glomerulosa (white line) is based on AS expression. Scale bar, 50 μm.