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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Clin Pharmacol Ther. 2010 Jan 20;87(3):286–293. doi: 10.1038/clpt.2009.222

Table 5. Investigator-assigned relative levels of medical risk and logistical burden for each of the four hypothetical studies.

Medical Risk Logistical
Burden
Investigational Drug Study Intermediate Low
Plant Extract Study Low High
HIV Study Intermediate Intermediate
Malaria Challenge Study High Intermediate