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. Author manuscript; available in PMC: 2011 Mar 23.
Published in final edited form as: Nature. 2010 Sep 23;467(7314):426–429. doi: 10.1038/nature09415

Figure 4. Tetrathionate respiration increases the abundance of S. Typhimurium in the intestinal lumen.

Figure 4

(A-C) Samples from a mouse colitis model (n indicated in B) four days after infection with S. Typhimurium (S. Tm) or mock-infection. (A) H&E stained cecal sections. Scale bar, 400 μm. (B) Blinded histopathology scoring showing averages (bars) and individual scores (circles). (C) Recovery of S. Typhimurium from colon contents. (D) Fraction of S. Typhimurium as percentage of the cecal bacterial population using 16S rRNA gene qRT-PCR (wild-type n=6, ttrA mutant n=6, mock-infected n=4). (C-D) Bars represent geometric means ± standard error. *, P < 0.05; **, P < 0.01.