Figure 3.

Dopamine release to trial-onset cues and reward delivery with fixed costs. A, Examples of dopamine release in the NAcc core to reward-related stimuli in the first, intermediate, and last trials. Current at the peak oxidation potential of dopamine is plotted as a function of time, with the inset showing the cyclic voltammogram identifying the detected current as dopamine. Below are two-dimensional pseudocolor plots of cyclic voltammograms over time. Rectangular dashed lines denote the cue onset, and square dashed lines denote the pellet delivery. B, Peak dopamine response in the NAcc core (n = 13) and shell (n = 9) to cue presentation. C, Peak dopamine response in the NAcc core and shell to pellet delivery.