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27-OHC activated ER stress. Western blots showing an increase in levels of caspase 12 (a) and gadd153 (b), two specific markers of ER stress. (c) Immunocytochemistry shows that gadd153 immunorectivity (green) is localized in nucleus (DAPI, blue) following treatment with 27-OHC (arrows). *p < 0.05, **p < 0.01 vs control; Bar, 20 μm.
