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. 2010 Sep 15;5:79. doi: 10.1186/1748-717X-5-79

Table 3.

The 3-year disease-free survival and locoregional control according to surgical margins

Surgical margin Disease-free survival (%) p Locoregional control (%) p
1 mm
 ≤1 mm 56 0.02* 59 <0.01*
 >1 mm 77 81
HR, univariate 0.4 (95% CI, 0.19-0.86) 0.02 0.4 (95% CI, 0.16-0.80) 0.01
HR, multivariate 0.2 (95% CI, 0.06-0.72) 0.02 0.2 (95% CI, 0.05-0.67) 0.01
2 mm
 ≤2 mm 59 <0.01* 64 <0.01*
 >2 mm 93 97
HR, univariate 0.1 (95% CI, 0.03-0.62) <0.01 0.1 (95% CI, 0.01-0.64) 0.02
HR, multivariate 0.1 (95% CI, 0.01-0.60) 0.01 0.1 (95% CI, 0.01-0.72) 0.02
3 mm
 ≤3 mm 67 0.06* 71 0.04*
 >3 mm 91 95
HR, univariate 0.3 (95% CI, 0.06-1.16) 0.08 0.2 (95% CI, 0.02-1.19) 0.07
HR, multivariate 0.2 (95% CI, 0.03-1.86) 0.17 0.3 (95% CI, 0.03-2.12) 0.21
4 mm
 ≤4 mm 69 0.13* 73 0.09*
 >4 mm 89 94
HR, univariate 0.3 (95% CI, 0.08-1.49) 0.15 0.2 (95% CI, 0.03-1.53) 0.12
HR, multivariate 0.3 (95% CI, 0.04-2.16) 0.22 0.3 (95% CI, 0.04-2.52) 0.28
5 mm
 ≤5 mm 72 0.36* 75 0.22*
 >5 mm 86 92
HR, univariate 0.5 (95% CI, 0.12-2.22) 0.37 0.3 (95% CI, 0.04-2.30) 0.25
HR, multivariate 0.5 (95% CI, 0.07-4.22) 0.56 0.6 (95% CI, 0.08-4.80) 0.63

Abbreviation: HR, hazard ratio; 95% CI, 95% confidence interval.

*, p values were calculated by using Kaplan-Meier method; other non-specified p values were calculated by using Cox proportional hazard regression.