A. Plasma HIV-1 RNA, log10 copies/mL, subject-specific trajectories shown in black, median values shown in blue. Vertical line shows study week at which last injection of pegylated-interferon occurred. The number of subjects with available data is shown at the top of the graph.
B. Plasma HIV-1 RNA changes from baseline, log10 copies/mL, trajectories of subject-specific changes in red (three subjects with reduced dosing) and black (all other subjects). Horizontal line at zero (no change from baseline); vertical line at last weekly injection of study drug.
C. Median changes in CD4+ T-cell count (solid red lines) and percent (broken blue lines) by study week, intervals represent 90% CIs around the medians.