Table 1.

Demographic and clinical features of the sample by diagnostic group. Data are shown as means ± standard deviation.

	HC1 n=21	HR n=21	MDD n=21
Age	12.2±2.4	12.8±2.8	11.8±2.6
Tanner scores	3.2±1.4	2.9±1.3	2.8±1.4
FGAS	90.4±5.3	75.2±7.7	62.6±10
CGAS	89.2±4.9	78.1±5.3	51.1±6.5
CDRS-R	18.6±1.8	20.8±1.7	58.1±5.8
Age of onset	—	—	10.8±3.0
Length of current depressive episode2	—	—	12.6±14.8
Suicide attempts, (n)	—	—	1
Ideation, 1-5 scale	—	—	2.2±0.8
Family history of MDD (n)	—	21	15
Comorbid psychiatric diagnosis (n)	—	—	15
ADHD	—	—	6
SAD	—	—	1
Generalized Anxiety	—	—	2
Dysthymic Disorder	—	—	4
Phobia	—	—	1
OCD	—	—	1

Note: Bold font indicates significant between-group differences. ADHD = Attention Deficit Hyperactivity Disorder; HC = Healthy Control; HR = High Risk; MDD = Major Depressive Disorder; OCD = Obsessive compulsive disorder; SAD = Seasonal Affective Disorder

¹n=20 for Family Global Assessment Scale (FGAS), Clinical Global Assessment Scale (CGAS), and Children's Depression Rating Scale – Revised (CDRS-R);

²in months