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. 2010 Sep 27;5(9):e13025. doi: 10.1371/journal.pone.0013025

Figure 1. Determination of τD by the ERG method from isolated mouse retina.

Figure 1

Recordings made from a retina perfused with bicarbonate-buffered Ringer at 37°C. (A) Family of responses to flashes of light in normal Ringer with 1 mM [Ca2+]. Flash strengths: 28, 87, 174, 348, 551, 874, 1390, 2200, 3480, 5510, 8740, 13900, 22000 Rh*. Data points used to determine τD ranged from 174 to 3480 Rh* (indicated by the horizontal line). (B) Response family in solution with 25 nM [Ca2+]free. Flash strengths were the same as in A and data points used to determine τD ranged from 874 to 8740 Rh* (indicated by the horizontal line). (C) Times for photoresponses to recover 20% (Tsat) from saturation plotted as a function of the natural logarithm of normalized flash strength. Data points from A (▪, normal Ringer with 1 mM Ca2+) and B (red ○, low-Ca2+ solution, 25 nM Ca2+). τD was 161and 231 ms in normal Ringer and in low Ca2+, respectively.