Table 1.
Placebo (n=36) |
Fluoxetine (n=34) |
Placebo (n=36) |
Fluoxetine (n=34) |
||||||
---|---|---|---|---|---|---|---|---|---|
% | % | % | % | Sig | |||||
Sex (% female) | 36.1% | 41.2% | 0.424 | ||||||
Ethnic (% white) | 58.3% | 55.9% | 0.836 | ||||||
Placebo (n=36) |
Fluoxetine (n=34) |
Placebo (n=36) |
Fluoxetine (n=34) |
||||||
Baseline | 12 Weeks (end of study) | ||||||||
Mean | s.d. | Mean | s.d. | Mean | s.d. | Mean | s.d. | Sig | |
BDI Total | 16.64 | 9.85 | 18.06 | 8.80 | 7.31 | 8.29 | 7.79 | 7.98 | 0.803 |
HAM-D 27 | 16.17 | 6.76 | 19.06 | 6.51 | 7.00 | 8.24 | 6.06 | 4.66 | 0.554 |
DSM Cannabis Abuse Crit Count | 1.19 | 0.86 | 1.35 | 1.01 | 0.47 | 0.65 | 0.59 | 0.79 | 0.476 |
DSM Cannab Depend Crit Count | 5.19 | 1.35 | 4.88 | 1.63 | 3.14 | 1.74 | 3.29 | 2.11 | 0.738 |
DSM Cann Ab+Dep Crit count | 6.39 | 1.71 | 6.24 | 2.26 | 3.61 | 1.92 | 3.88 | 2.51 | 0.612 |
DSM Alcohol Abuse Crit Count | 0.33 | 0.72 | 0.32 | 0.59 | 0.14 | 0.35 | 0.24 | 0.50 | 0.349 |
DSM Alcohol Depend Crit Count | 1.00 | 1.43 | 1.24 | 1.62 | 0.75 | 1.20 | 0.65 | 0.81 | 0.678 |
DSM Alco Ab+Dep Crit Count | 1.33 | 1.90 | 1.56 | 2.11 | 0.89 | 1.33 | 0.88 | 1.17 | 0.983 |
DSM Current MDD Crit Count | 7.00 | 1.24 | 6.97 | 1.31 | 5.39 | 2.22 | 4.53 | 2.56 | 0.138 |
Total Drinks per Week | 6.74 | 7.99 | 8.35 | 10.06 | 5.69 | 8.17 | 8.68 | 12.41 | 0.702 |
Days of Alcohol Use per Week | 1.38 | 1.24 | 1.50 | 1.16 | 1.24 | 1.30 | 1.49 | 1.44 | 0.982 |
Heavy Drinking Days per Week | 0.63 | 0.91 | 0.77 | 0.98 | 0.51 | 0.81 | 0.74 | 1.07 | 0.367 |
Average drinks per drinking occasion in past month |
4.21 | 2.36 | 4.95 | 3.31 | 3.20 | 2.73 | 3.88 | 3.87 | 0.399 |
Days used cannabis in past week | 4.35 | 1.93 | 4.61 | 2.18 | 3.10 | 2.27 | 3.88 | 2.60 | 0.182 |
Key: BDI, Beck Depression Inventory; HAM-D 27, Hamilton Depression Rating Scale, 27-item version; DSM, Diagnostic and Statistical Manual