Table 4.
Unadjusted and Adjusted* Odds Ratios for the association between various Somatic Disease Factors and incident Fibromyalgia in Women, the Adventist Health Study, California. 1976–2002 (N=3,136)
| Non-cases | No. | Unadjusted | Adjusted* | |||
|---|---|---|---|---|---|---|
| N=3,000 | N=136 | OR | 95% CI | OR | 95% CI | |
| n (%) | n (%) | |||||
| No. of allergies§ | ||||||
| 0 | 1,461 (48.7) | 42 (30.9) | 1.00 | Referent | 1.00 | Referent |
| 1 | 899 (30.0) | 43 (31.6) | 1.66 | 1.08–2.57 | 1.94 | 1.19–3.14 |
| ≥ 2 | 570 (19.0) | 47 (34.6) | 2.87 | 1.87–4.40 | 3.39 | 2.08–5.51 |
| P(trend)<0.0001 | P(trend)<0.0001 | |||||
| Peptic ulcer | ||||||
| No | 2,697 (89.9) | 113 (83.1) | 1.00 | Referent | 1.00 | Referent |
| Yes | 210 (7.0) | 17 (12.5) | 1.93 | 1.14–3.28 | 1.93 | 1.05–3.56 |
| Hyperemesis gravidarum | ||||||
| Never | 1,710 (57.0) | 65 (47.8) | 1.00 | Referent | 1.00 | Referent |
| Some pregnancis | 450 (15.0) | 24 (17.6) | 1.39 | 0.86–2.24 | 2.24 | 0.81–2.39 |
| All pregnancies | 383 (12.8) | 27 (19.9) | 1.77 | 1.11–2.82 | 1.74 | 1.03–2.94 |
| P(trend)=0.01 | P(trend)=0.03 | |||||
| Hypertension | ||||||
| No | 2,544 (84.8) | 112 (82.4) | 1.00 | Referent | 1.00 | Referent |
| Yes | 379 (12.6) | 18 (13.2) | 1.08 | 0.65–1.80 | 1.65 | 0.93–2.90 |
| Breast cyst or lump | ||||||
| No | 2,338 (79.6) | 97 (71.3) | 1.00 | Referent | 1.00 | Referent |
| Yes | 586 (19.5) | 32 (23.5) | 1.32 | 0.87–1.98 | 1.28 | 0.80–2.04 |
| Rheumatic arthritis | ||||||
| No | 2,810 (93.7) | 124 (91.2) | 1.00 | Referent | 1.00 | Referent |
| Yes | 87 (2.9) | 4 (2.9) | 1.04 | 0.38–2.88 | 1.15 | 0.35–3.76 |
*
adjusted for age, BMI, , education, work for pay, marital status
§
“allergies” include any allergic diseases, such as asthma, hay fever, allergy to medicine, chemicals, bees, plants.