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. Author manuscript; available in PMC: 2011 Nov 25.
Published in final edited form as: Mol Cell Endocrinol. 2010 May 2;329(1-2):47–55. doi: 10.1016/j.mce.2010.04.025

Fig. 2.

Fig. 2

Crystal structure of the FSH-FSHR ECD complex. Two views of the complex, rotated by 90° about the vertical axis, are shown. The ECD is presented as red, and the FSH α and β chains are in green and cyan, respectively. The structure of the complex depicts the large contact surface area accompanying hormone-receptor binding and shows that both subunits contribute to receptor interaction. The figure was kindly provided by Dr. W.A. Hendrickson and is reproduced with permission from Macmillan Publishers Ltd.: Nature (Fan and Hendrickson, 1995).