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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: J Thorac Oncol. 2010 Oct;5(10):1551–1558. doi: 10.1097/JTO.0b013e3181e9da60

Figure 1.

Figure 1

Representative pictures of EGFR expression by immunohistochemical staining (40× magnification). A. DNA sequence E746-A750 deletion specimen stained with the E746-A750 specific antibody. Immunoreactivity is positive in the tumor cells but absent in non-tumor cells. B. DNA sequence L858R point mutation case. The tumor cells show no immunoreactivity with the E746-A750 specific antibody. C. L858R point mutation tumor showing tumor cells positive for L858R specific antibody. D. E746-A750 mutation case displaying no immunoreactivity in the tumor or non-tumor cells with the L858R specific antibody.