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Detection capabilities for the EGFR mutation-specific antibodies.
| Sensitivity | Specificity | Accuracy | PPV | NPV | |
|---|---|---|---|---|---|
| E746-A750 | 81.8% | 100% | 97.1% | 100% | 96.7% |
| All exon 19 mt | 50% | 100% | 87.1% | 100% | 85.2% |
| L858R* | 75% | 96.6% | 92.9% | 81.8% | 94.9% |
| E746-A750 + L858R | 78.3% | 95.7% | 90% | 90% | 90% |
| Any mutation of All Ex19 mt + L858R | 43.9% | 99.9% | 64.3% | 90% | 54% |
PPV=Positive predictive values, NPV=Negative predictive values
Including 2573 T>K (K=G or T)
