Figure 2A. 45Calcium Uptake in Chick Cultures Treated with Apoptogen. The treatment of chick cultures with camptothecin completely inhibited mineralization, and 45Ca uptake values were similar to non-mineralizing control (1P) cultures.
Figure 2B. 45Calcium Uptake in Murine Cultures Treated with Apoptogen. Both staurosporine and camptothecin caused an increase in the rate and extent of 45Ca uptake in murine cultures. Treatment with staurosporine resulted in the highest amount of mineral accretion, with values about 2.5 times that of control mineralizing (4P) cultures.