TABLE II.
Recurrence and relative risk of isolated oral cleft, Denmark 1956 – 2005
| Designation of Relationship | Number Affected (n) |
Total (N) |
Recurrence Risk (%) [95% confidence interval] |
Relative Risk*, [95% confidence interval] |
|---|---|---|---|---|
| Background population prevalence | 6,194 | 3,394,923 | 0.18 | Reference |
| Offspring of affected parents (background population) |
234 | 6,642 | 3.5 [ 3.1 ; 4.0 ] | 19 [ 17 ; 22 ] |
| Offspring of affected discordant twins |
2 | 110 | 1.8 [ 0.22 ; 6.4 ] | 10 [ 1.2 ; 35 ] |
| Offspring of non-affected discordant twins |
3 | 129 | 2.3 [ 0.48 ; 6.7 ] | 13 [ 2.6 ; 36 ] |
Significant if p < 0.05, in bold
*
Compared to the risk in the background population born in the same time period