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. Author manuscript; available in PMC: 2011 Oct 1.
Published in final edited form as: Am J Med Genet A. 2010 Oct;152A(10):2468–2474. doi: 10.1002/ajmg.a.33608

TABLE III.

Twin pairs discordant for isolated oral cleft. Zygosity stratification of recurrence risk and relative risk, Denmark 1956 to 2005

Twin parents status Recurrence Recurrence risk (%)
[95% confidence interval]
Relative risk*,
[95% confidence interval]


Zygosity Oral Cleft Number
Affected (n)
Total (N)
Monozygotic No 2 26 7.7 [ 0.95 ; 25 ] 42 [ 5.3 ; 140 ]
Yes 0 16 0 0

Dizygotic No 1 103 0.97 [ 0.025 ; 5.3 ] 5.3 [ 0.17 ; 29 ]
Yes 2 90 2.2 [ 0.27 ; 7.8 ] 12 [ 1.7 ; 43 ]

Significant if p<0.05, in bold

*

Compared to the risk in the background population born in the same time period