Table 3.

Characteristics of Initial 6 Anti-RNA polymerase I/III positive subjects

Subject #	Gender	Malignancy	Scleroderma Duration at Cancer Diagnosis (years)	RP Duration at Cancer Diagnosis (years)	mRSS*	Scleroderma Complications**
1	Female	Breast invasive ductal carcinoma	−2.0	0.7	42	Renal crisis ILD
2	Female	Lung small cell carcinoma	−1.0	0	47	ILD
4	Female	Ovarian poorly differentiated metastatic carcinoma	−1.3	−0.3	21	Renal crisis Myopathy
9	Female	Non-Hodgkin lymphoma	0.8	0.5	14	Myopathy PAH
13	Female	Breast invasive ductal carcinoma	1.3	1.0	30	None
35	Female	Breast ductal carcinoma in situ	−2.0	−2.4	48	None

^*Maximal mRSS during disease course

^**Complications evaluated include renal crisis, myopathy, ILD, and PAH.

Abbreviations: RP – Raynaud’s phenomenon, mRSS – modified Rodnan skin score, ILD – interstitial lung disease, PAH – pulmonary arterial hypertension