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. Author manuscript; available in PMC: 2011 Oct 1.

Published in final edited form as: Exp Neurol. 2010 Jul 27;225(2):423–429. doi: 10.1016/j.expneurol.2010.07.020

Fig. 2 — Levels and activities of plasma membrane redox enzymes NADH-AFR and NQO1 are reduced in PMs from brains of 3xTgAD mice. The PM fractions isolated from the indicated brain regions were used to measure activity and expression levels of NADH-ADR reductase (A) and NQO1 (B). Immunoblot analysis using NADH-AFR or NQO1 was performed and representative blots were shown. Values are the means±SEM; n=6, by using pooled tissue from three mice per group. *, P<0.01 compared with the value for WT. CTX, cerebral cortex; HIP, hippocampus; STR, striatum; CER, cerebellum; BS, brainstem; W, WT; T, 3xTgAD.

Fig. 2 — Levels and activities of plasma membrane redox enzymes NADH-AFR and NQO1 are reduced in PMs from brains of 3xTgAD mice. The PM fractions isolated from the indicated brain regions were used to measure activity and expression levels of NADH-ADR reductase (A) and NQO1 (B). Immunoblot analysis using NADH-AFR or NQO1 was performed and representative blots were shown. Values are the means±SEM; n=6, by using pooled tissue from three mice per group. *, P<0.01 compared with the value for WT. CTX, cerebral cortex; HIP, hippocampus; STR, striatum; CER, cerebellum; BS, brainstem; W, WT; T, 3xTgAD.

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