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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Pediatrics. 2010 May 10;125(6):e1475–e1482. doi: 10.1542/peds.2009-1796

Table 1.

Risk/Benefit Trade-offs in the Four Hypothetical Scenarios

Scenario Risk/Benefit Drug A (%) Drug B (%) Incremental change (%)
No trade-off Pain relief 60 75 +15
Itching 25 20 −5
Slowed breathing 7 5 −2
Risk 1 Pain relief 60 55 −5
Itching 25 20 −5
Slowed breathing 7 5 −2
Risk 2 Pain relief 60 55 −5
Itching 25 12 −13
Slowed breathing 7 5 −2
Risk 3 Pain relief 60 55 −5
Itching 25 20 −5
Slowed breathing 7 3 −4