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. Author manuscript; available in PMC: 2011 Apr 15.
Published in final edited form as: J Infect Dis. 2010 Apr 15;201(8):1121–1131. doi: 10.1086/651454

Table 3.

Factors at time of ART initiation associated with mortality during the first 39 weeks of treatment

Kaplan-Meier results Cox Proportional Hazards results

died alive probability of
dying
log
rank p-
value
crude
Hazard
Ratio
95% CI p-value adjust
ed
Hazard
Ratio
95%CI p-value
Total 32 222 14.0
Sex
 male 18 114 14.7 ref ref
 female 14 108 13.2 0.547 0.81 0.40-1.62
Age in months
 < 12 27 148 17.6 2.54 0.98-6.61 0.055 2.44 0.92-6.45 0.073
 ≥ 12 5 74 6.4 0.047 ref ref ref ref
Weight-for-age z-score a
 > −2 8 103 8.1
 > −3 to −2 3 53 6.5
 > −4 to −3 8 34 20.3
 ≤ −4 13 32 30.8 0.001 1.75 1.30-2.36 0.0002 1.61 1.19-2.19 0.002
HIV RNA in copies/ml *
 < 750,000 3 76 3.8 ref ref ref ref
 ≥ 750,000 29 137 19.3 0.005 4.71 1.44-
15.48
0.011 3.22 0.97-
10.78
0.057
Pretreatment CD4%
 < 15 17 78 19.1 1.97 0.99-3.95 0.055 1.72 0.84-3.50 0.136
 ≥ 15 15 144 11.1 0.051 ref ref ref ref
TB treatment
 never 16 139 11.2 ref ref
 Start before ART 8 54 13.9 1.10 0.47-2.56
 Start after ART 8 29 22.4 0.321 1.88 0.80-4.41
a

in Cox proportional hazard analyses included as continues variable

*

9 children did not have a pre-treatment viral load