Fig. 4.

Different expression and correlation of TLRs, AMPs and VDR in psoriasis lesional skin in the serum vitamin D deficient (VDD) group compared to the serum vitamin D sufficient (VDS) group. (A) HBD2 and LL-37 expression are significantly downregulated in the VDD group compared to the VDS group. (B, C) Negative correlation is found between TLR2 and VDR expression in the VDD groups (B; r=0.272, P=0.174), however, significant positive correlation is noted in the VDS groups (C; r=0.146, P=0.048).

^*P=0.041; ^†P=0.000. PA/EA, Ab positive area per measured epidermal area.