Table 2.
Sequence differences observed among phleboviruses
| Comparison | L segment | M segment | Ns gene | N gene | ||||
|---|---|---|---|---|---|---|---|---|
| Mean (%) | SD (%) | Mean (%) | SD (%) | Mean (%) | SD (%) | Mean (%) | SD (%) | |
| Within RVFV | 8.3 | 0.2 | 6.8 | 0.3 | 2.6 | 0.3 | 2.2 | 0.3 |
| Amino acid difference | 1.6 | 0.2 | 3.9 | 0.4 | 1.8 | 0.4 | 0.4 | 0.2 |
| Within TOSV | 4.7 | 0.1 | 2.9 | 0.1 | 8.5 | 0.6 | 3.2 | 0.4 |
| Amino acid difference | 2.6 | 0.1 | 0.8 | 0.1 | 5.3 | 0.8 | 0.0 | 0.0 |
| Between GRV and MASV | 4.3 | 0.2 | 37.6 | 0.8 | 4.9 | 0.7 | 3.1 | 0.6 |
| Amino acid difference | 1.1 | 0.2 | 39.7 | 1.3 | 3.2 | 0.3 | 0.4 | 0.4 |
| Between GRV and TOSV | 26.8 | 0.5 | 42.9 | 0.9 | 48.6 | 1.7 | 25.6 | 1.6 |
| Amino acid difference | 17.1 | 0.8 | 44.1 | 1.7 | 54.9 | 2.6 | 16.2 | 2.5 |
| Between GRV and RVFV | 41.8 | 0.6 | 54.5 | 0.7 | 69.4 | 1.6 | 44.1 | 1.7 |
| Amino acid difference | 45.4 | 1.1 | 65.5 | 0.3 | 87.0 | 2.0 | 49.8 | 0.3 |
| Between MASV and TOSV | 26.5 | 0.5 | 42.5 | 0.9 | 48.4 | 1.6 | 24.3 | 1.6 |
| Amino acid difference | 17.1 | 0.8 | 44.0 | 1.7 | 53.1 | 2.6 | 15.7 | 2.5 |
| Between MASV and RVFV | 41.7 | 0.6 | 53.9 | 0.7 | 68.6 | 1.7 | 44.1 | 1.7 |
| Amino acid difference | 45.6 | 1.1 | 64.7 | 1.3 | 86.6 | 2.0 | 49.4 | 0.3 |
| Between TOSV and RVFV | 42.6 | 0.6 | 55.5 | 0.9 | 67.6 | 1.6 | 45.6 | 1.9 |
| Amino acid difference | 45.6 | 1.1 | 64.1 | 1.6 | 83.4 | 2.1 | 49.1 | 3.3 |
Percent similarity of the sequences is shown. To estimate the evolutionary divergence over sequence pairs between groups, the average number of nucleotide differences per site over all sequence pairs between groups and among groups was calculated. Standard error estimates are shown in the second column and were obtained by a bootstrap procedure (500 replicates). For each pairwise sequence comparison, all positions containing alignment gaps and missing data were eliminated. SD = standard deviation.