Table 1.
Patient population for the study
| Group and populations | Number of patients | Age range (yrs) | MF count | CFA (Og4C3) | ||
|---|---|---|---|---|---|---|
| Pre | Post | Pre | Post | |||
| INDIA–Wuchereia bancrofti | ||||||
| Screening* | 172 | |||||
| Endemic normals | 59 | 21–51 | 0 | – | 7 (2–35) | – |
| Asymptomatic microfilaraemics | 58 | 17–58 | 180 (1–1,350) | – | 224,614 (4–4,198,147) | – |
| Chronic lymphedema | 55 | 18–65 | 0 | – | 22 (1.3–54) | – |
| MALI–Wuchereria bancrofti and Mansonella perstans | ||||||
| Pre- and post-treatment (12 mo) | 60 | |||||
| Asymptomatic microfilaraemic (doxycycline) | 31 | 19–64 | 476 (17–3,196) | 0 | 1,323 (612–2862) | 572 (207–1,077) |
| Asymptomatic microfilaraemic (no treatment) | 29 | 19–65 | 328 (0–6,222) | 198 (0–3,026) | 401 (162–993) | 192 (73–506) |
*
Subset of the population (36 from each group) has been assayed for lymphangiogenic panels.