. Author manuscript; available in PMC: 2011 Sep 15.

Published in final edited form as: J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Jul 29;878(26):2457–2460. doi: 10.1016/j.jchromb.2010.07.016

Table 2.

Changes in urinary menadione excretion in response to 3 years of 500 μg/day (1109 nmole/day) of phylloquinone (PK) supplementations. Values are presented as mean± SD.

MD (nmole/24 hours urine excretion)
	PK –Supplemented Group (n=186)	Control Group (n=181)	P Value^A
Baseline	12.55± 9.53 ^m	13.26± 10.11 ^m	0.4893
3 Years^B	31.59± 29.73 ⁿ	12.27± 10.67 ^m	<0.0001
Δ (3 Years- Baseline)	19.05± 28.29	−0.98± 12.60	<0.0001

P value based on student’s t test adjusted for multiple comparisons.

Paired student’s t test: PK group at 3 years is significantly different from baseline.