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. Author manuscript; available in PMC: 2010 Sep 28.
Published in final edited form as: Neuroimage. 2008 Oct 18;45(2):260–266. doi: 10.1016/j.neuroimage.2008.09.052

Table 2.

Correlations between longitudinal changes in pattern expression, global values, and clinical motor ratings

PDRP Networka Positive Subnetwork Negative Subnetwork Early Networkb GMR UPDRS
PDRP Networka 0.85c, <0.0001 0.80, <0.0001 0.98, <0.0001 −0.23, 0.25 0.62, 0.004
Positive Subnetwork 0.85c, <0.0001 0.43, 0.03 0.88, <0.0001 −0.11, 0.59 0.62, 0.004
Negative Subnetwork 0.80, <0.0001 0.43, 0.03 0.75, <0.0001 −0.28, 0.16 0.53, 0.02
Early Networkb 0.98, <0.0001 0.88, <0.0001 0.75, <0.0001 −0.14, 0.51 0.59, 0.006
GMR −0.23, 0.25 −0.11, 0.59 −0.28, 0.16 −0.14, 0.51 −0.32, 0.17
UPDRS 0.62, 0.004 0.62, 0.004 0.53, 0.02 0.59, 0.006 −0.32, 0.17
a

PD-related spatial covariance pattern (PDRP) identified by SSM/PCA of FDG PET scans from a combined group of 33 mild-moderate PD patients and 33 healthy subjects (Ma et al., 2007).

b

Spatial covariance pattern identified by SSM/PCA of FDG PET scans from a combined group of 24 early stage PD patients and 24 healthy subjects (see Analysis 2 in text)

c

Bland-Altman within-subject correlation coefficients and associated p-values for comparisons of longitudinal changes in pattern expression with concurrent changes in PDRP subnetwork scores, GMR, and UPDRS motor ratings (see text).

PDRP = Parkinson’s disease-related pattern; GMR = global metabolic rate; UPDRS = Unified Parkinson’s Disease Rating Scale