Table 1.
| |
---|---|
entry | producta yield |
1 | |
2 | |
3 | |
4 | |
5 | |
6 | |
7 | |
8 | |
9 | |
10 | |
11 | |
12 |
5% Pd(OAc)2, 10% RuPhos, 3 equiv K2CO3, toluene/H2O, 85 °C, 22 h
b 5% Pd(OAc)2, 10% SPhos, 3 equiv K2CO3, toluene/H2O, 85 °C, 22 h
| |
---|---|
entry | producta yield |
1 | |
2 | |
3 | |
4 | |
5 | |
6 | |
7 | |
8 | |
9 | |
10 | |
11 | |
12 |
5% Pd(OAc)2, 10% RuPhos, 3 equiv K2CO3, toluene/H2O, 85 °C, 22 h
b 5% Pd(OAc)2, 10% SPhos, 3 equiv K2CO3, toluene/H2O, 85 °C, 22 h