Table 1.
Tissue ingrowth and continuity (H&E) | Myelinated fibers (LFB) | Astrocyte immigration (GFAP) | Axonal infiltration (Tuj1) | |
---|---|---|---|---|
Cylinder (n = 3) | − | − | − | − |
Tube (n = 3) | + | − | − | + |
Channel (n = 3) | + | − | + | + |
Open-path without core (n = 3) | + + | + + | + | + + |
Open-path with core (n = 3) | + + | + + + | + + | + + + |
Presence of staining or labeling within the defect site in one or more section of each replicate is indicated by a (+) for each replicate animal, whereas a (−) indicates none found. In the case of tissue ingrowth and continuity, fibrous tissue continuity between stumps and scaffold on both ends was assigned a (+), whereas discontinuity in all groups received a (−).