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. 2010 Sep 28;5(9):e13070. doi: 10.1371/journal.pone.0013070

Figure 6. Pipeline meta-algorithm developments.

Figure 6

(Top Panel) This figure shows the LONI Pipeline implementation of the image registration meta-algorithm (IRMA). The four different registration algorithms AIR Linear, AIR Warp, FLIRT and MINC Tracc are present as individual nodes in this pipeline. Parameter sets specifying altogether 186 different runs for these algorithms are stored as editable lists within the LONI Pipeline environment. (Bottom Panel) Parallel-coordinates plot showing the rank-transformed metrics for one input image. Eleven distance metrics were employed to evaluate all 186 alignment instances. The results of the IRMA analysis illustrate that the FLIRT family performed consistently better than the other alignment methods for this input volume. The EDI (Entropy of Difference of Intensities) and the Woo (Woods' coefficient) metrics disagree somewhat with the other 9 metrics.