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. Author manuscript; available in PMC: 2011 Sep 23.
Published in final edited form as: Neuron. 2010 Sep 23;67(6):929–935. doi: 10.1016/j.neuron.2010.08.022

Figure 1. Atrophy of Purkinje cell dendrites in ATXN1[30Q]-D776 mice.

Figure 1

Calbindin immunofluorescent confocal images taken at 60x with 150x enlargements (inserts) from the region of the molecular layer indicated by the white box.

(A) Purkinje cell dendritic tree of 12-week-old wt/FVB mice having a molecular layer thickness of 184 μm, ± 2.6 (n = 6).

(B) Purkinje cell dendritic tree of 12-week-old ATXN1[30Q]-S776 homozygous mice having a molecular layer thickness of 162 μm, ± 3.5 (n = 6).

(C) Purkinje cell dendritic tree of 12-week-old ATXN1[82Q]-S776 mice having a molecular layer thickness of 157 μm, ± 2.7 (n = 5).

(D) Purkinje cell dendritic tree of 12-week-old ATXN1[30Q]-D776 mice having a molecular layer thickness of 159 μm, ± 2.4 (n = 4).