Table 1.

Number of mice that survived MMC-treatments after LV-mediated intrafemoral gene transfer.

	Wild type		Fa nc C −/−		Fa nc A −/−
		Pre-conditioned*		Pre-conditioned*		Preconditioned
	5/5	6/6	5/5	6/6	3/3	3/4¶
Weekly MMC (0.3 mg /kg)†	5/5	6/6	5/5	5/6‡	0/3	0/4

Number of mice that survived/number of mice IF-injected with EGFP-FancC recombinant viral particles.

* Mice were pre-conditioned with MMC (0.3 mg/kg) 4 days prior to IF injection.

^† Weekly treatment with MMC for 15 weeks.

^‡ 1 FancC ^−/− mouse died due to bleeding during blood collection.

^¶ 1 FancA ^−/− mouse died 15 days following IF injection from a mishap unrelated to vector administration.