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. Author manuscript; available in PMC: 2011 Oct 31.
Published in final edited form as: Int J Pharm. 2010 Aug 7;399(1-2):148–155. doi: 10.1016/j.ijpharm.2010.07.057

Figure 7.

Figure 7

ND protects HepG2 cells from AMB/DOC cytotoxicity. HepG2 cells in 24 well plates were incubated for 18 hr with equivalent concentrations of ND-empty, ND-AMB or ND-AMB+ normalized by protein (all 4.1 µg/mL apoA-I and 0, 2.6 or 10.3 µg/mL AMB, respectively) in the absence (white bars) or presence (black bars) of AMB/DOC (40 µg/mL). (A) Cell viability was determined using the MTT assay. (B) Cellular integrity was assessed by LDH release. Measurements are representative of two independent experiments performed in triplicate. **p<0.001, ***p<0.0001.