Table 3.

Peripapillary RNFL and macular thinning with increasing duration of disease. Independent of age and a history of optic neuritis, multiple sclerosis patients with a longer duration of disease had significantly thinner peripapillary RNFL measurements. No such correlation was noted with respect to macular thickness measurements (β represents the correlation coefficient)

RNFL	β (13–60 months)	95% CI	P	β (>60 months)	95% CI	P
Temporal	−7.14	−16.43, 2.16	0.13	−2.45	−11.03, 6.13	0.58
Superior-temporal	−19.67	−36.14, −3.20	0.02	−16.17	−31.68, −0.67	0.04
Superior-nasal	−7.45	−24.20, 9.30	0.38	−17.85	−32.37, −3.32	0.02
Nasal	−0.35	−13.16, 12.46	0.96	−10.82	−21.58, −0.06	0.05
Inferior-nasal	3.35	−12.01, 18.70	0.67	−13.26	−29.96, 3.44	0.12
Inferior-temporal	−8.95	−23.56, 5.67	0.23	−13.50	−25.68, −1.32	0.03
Superior	−13.20	−27.11, 0.71	0.06	−16.87	−30.03, −3.71	0.01
Inferior	−3.00	−15.19, 9.18	0.63	−13.49	−24.09, −2.90	0.01
Average	−5.80	−15.69, 4.08	0.25	−10.89	−18.97, −2.82	0.008
Macular thickness	β (13–60 months)	95% CI	P	β (>60 months)	95% CI	P
Central subfield	−4.80	−19.22, 9.61	0.51	−4.80	−17.52, 7.90	0.46
Inner temporal	−5.58	−17.24, 6.08	0.35	−7.18	−17.23, 2.88	0.16
Inner superior	−9.71	−22.72, 3.31	0.14	−10.64	−22.19, 0.90	0.07
Inner nasal	−6.60	−19.75, 6.46	0.32	−10.10	−21.08, 0.84	0.07
Inner inferior	−6.80	−20.01, 6.33	0.31	−7.00	−19.01, 5.01	0.25
Outer temporal	−6.69	−18.16, 4.77	0.25	−6.95	−16.97, 3.08	0.18
Outer superior	−8.59	−22.14, 4.96	0.21	−10.13	−22.33, 2.07	0.10
Outer nasal	−6.79	−19.70, 6.12	0.30	−9.09	−21.62, 3.43	0.16
Outer inferior	−7.92	−20.24, 4.41	0.21	−7.39	−19.27, 4.50	0.22

Abbreviations: RNFL, retinal nerve fiber layer; CI, confidence interval.