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. 2010 Oct;136(4):367–387. doi: 10.1085/jgp.201010430

Figure 9.

Figure 9.

C276A prevents the PCMBS-mediated modulation on channel kinetics. Activation and deactivation kinetics were estimated with Ca2+ jump experiments using Ca2+i concentrations 0.5, (A) 0.7, (B) 1.0, (C) and 10 µM (D) in the absence (black trace) and presence (red trace) of PCMBS as described in Fig. 4. Activation (E) and deactivation (F) rates were estimated by fitting activation and deactivation records with an exponential function and reported as a time constant (τ-on and τ-off) in the absence (•) and presence (○) of PCMBS, see also Table I.