Table II.

The tilt in the TM helices is shown for each of the open-state models as well as the magnitude of structural change required to move from the closed state to each open state

Model	Tilt TM1	Tilt TM2	RMSD in subunit	RMSD in pentamer
			Å	Å
Closed	37.2	34.4
0 dyn/cm	52.5	39.0	8.1	11.5
5 dyn/cm	56.3	42.4	9.9	12.0
60 dyn/cm	59.8	47.0	8.9	12.7
Meyer (32)	51.2	54.5	12.6	17.7
Sukharev (27)	71.5	56.3	9.5	33.2

The structural change is determined by aligning either a single subunit to a subunit in the closed structure, or the whole pentamer to the closed pentameric structure, and presented as a root mean-square deviation (RMSD).